Advanced Cardiovascular Life Support (ACLS) Practice Exam

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What is the recommended second dose of amiodarone for a patient in refractory ventricular fibrillation?

  1. 150 mg IV push

  2. 300 mg IV push

  3. 75 mg IV push

  4. 100 mg IV push

The correct answer is: 150 mg IV push

In cases of refractory ventricular fibrillation, the recommended second dose of amiodarone is 150 mg administered as an intravenous push. This guideline comes from advanced cardiovascular life support protocols, highlighting the importance of optimizing defibrillation and medication in managing acute cardiac emergencies. Administering 150 mg is consistent with established guidelines, which recommend this dosage specifically after the initial dose of 300 mg if the patient remains in ventricular fibrillation. This step is crucial as it helps to optimize the chances of restoring a normal heart rhythm by providing an effective antiarrhythmic agent without overwhelming the patient’s system. Lower doses, such as 75 mg or 100 mg, are not standard for this situation and would be inadequate for the severity of refractory ventricular fibrillation. Therefore, the correct response emphasizes the role of effective therapeutic doses in critical care settings, aiding in the restoration of a stable cardiac rhythm.