Advanced Cardiovascular Life Support (ACLS) Practice Exam 2025 – Your Comprehensive All-in-One Guide to Exam Success!

The maximum dose of amiodarone that can be administered during a single cardiac arrest episode is 300 mg for the first dose, with the option to administer an additional 150 mg if necessary. This guideline is based on the Advanced Cardiovascular Life Support (ACLS) protocols for managing a patient experiencing ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT).

When a patient is in cardiac arrest due to VF or pulseless VT, the administration of amiodarone is indicated to help stabilize the cardiac rhythm. The initial dose of 300 mg is given intravenously or intraosseously. If the patient remains in either of these arrhythmias after the first dose, a subsequent dose of 150 mg may be administered.

This dosing strategy takes into account both the efficacy of amiodarone in converting these life-threatening arrhythmias into a more stable rhythm and the potential side effects of the drug. It ensures that responders can provide a therapeutic dose while minimizing the risk of toxicity. Other doses listed are either insufficient or exceed recommended limits for acute administration in this specific context.